The IL23 axis plays a key role in the pathogenesis of IBD.
نویسندگان
چکیده
Exciting new results from a genetic study in humans and functional studies in mice have pinpointed interleukin 23 (IL23) and its receptor as a key pathway in the pathogenesis of inflammatory bowel disease (IBD). These findings reveal a hitherto unappreciated role for the IL23 axis in intestinal inflammation and may open new avenues for development of therapeutic strategies in IBD.
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ورودعنوان ژورنال:
- Gut
دوره 56 10 شماره
صفحات -
تاریخ انتشار 2007